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siRNAs have been shown to act as potent inducers of RNAi in cultured mammalian cells. Many investigators have suggested that siRNAs may have evolved as a normal.
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Ionizable polymeric micelles (IPMs) for efficient siRNA delivery
To ensure that the observed reduction of GFP signals was not due to the toxic effects of SWNT-PL-PEG-S-S-siGFP or SWNT-PL-PEG-siGFP conjugates, the cytotoxic effects of SWNT-PL-PEG-S-S-siGFP or SWNT-PL-PEG-siGFP conjugates on these cell lines were determined using the LDH release assay at 72 h after treatment. As shown in Supplement Figure S1. Neither the SWNT-PL-PEG-S-S-siGFP nor SWNT-PL-PEG-siGFP conjugates significantly affected cell viability.Sirna Sex Escort
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